Causes of idiopathic constipation in Thai patients: associations between the causes and constipation symptoms as defined in the Rome II criteria.

UNLABELLED The authors investigated 103 consecutive Thai patients (29M, 74F age 50 +/- 20) with chronic idiopathic constipation (symptom duration; median 5 yr, range 0.25-45 yr) as defined by Rome II criteria using colonic transit test, anorectal manometry, and balloon expulsion tests. Constipation symptoms were evaluated by a questionnaire. RESULTS There were 30, 14, 11, and 48 patients who fulfilled the criteria of anorectal dysfunction, colonic inertia, anorectal dysfunction plus colonic inertia, and the normal transit constipation, respectively. The proportion of female gender in the normal transit constipation group (F:M=37:11) was significantly greater than the anorectal dysfunction group (16.14, p<0.05%). Patients with colonic inertia and colonic inertia plus anorectal dysfunction had a higher prevalence of infrequent bowel movement compaired to anorectal dysfunction and normal transit constipation (p<0.001). The prevalence of straining, hard stool, incomplete evacuation, sense of anal obstruction, and use of manual maneuver to facilitate defecation, were not different among the constipation subgroups (p>0.05). CONCLUSIONS Prevalence of pathophysiologic conditions associated with idiopathic constipation in Thai patients are similar to Western countries. 29%, 13%, and 11% of Thai patients with idiopathic constipation were associated with anorectal dysfunction, colonic inertia, and anorectal dysfunction plus colonic inertia, respectively. Among the 6 constipation symptoms defined by Rome II criteria, only infrequent bowel movements was associated with delayed colonic transit.